An inflammatory arthritis that can affect any age and involving the hands, wrists, elbows, shoulders and knees with pain, inflammation, and morning stiffness lasting greater than 30 minutes. It frequently responds to steroids (prednisone or Medrol) but ultimately requires treatment with DMARDs such as Plaquenil, sulfasalazine, methotrexate, or leflunomide or biologic response modifiers such as etanercept (Enbrel), adalimumab (Humira), Actemra, Orencia, or Xeljanz.